Shandong Bona Biotechnology Group Co., Ltd. has utilized its professional advantages in membrane separation technology for many years, and after repeated experiments and demonstrations, has successfully developed and produced a plasma protein membrane concentration process. Not only does it reduce the production cost of plasma protein powder, but it also reduces the ash content of plasma protein powder and improves the quality of the product.

Membrane concentration process for plasma protein:

Plasma storage tank → Pretreatment system → Ultrafiltration membrane feed pump → Ultrafiltration membrane filtration system → Ultrafiltration membrane high-pressure circulation pump → Ultrafiltration membrane concentration and separation system → Concentrated plasma storage tank

1、 Design basis

Select a certain molecular weight ultrafiltration membrane and use a unique technology to concentrate and separate the plasma separated by a high-speed tube centrifuge, removing some moisture and ash. This concentration system is designed with continuous feeding and discharging, which is filtered by the pre-treatment system before entering the membrane system. The plasma is transported by the feed pump to the filtration system configured by the ultrafiltration membrane itself, and then enters the high-pressure pump. The plasma concentration is achieved through the pressure increase of the high-pressure pump. The concentrated plasma is sent to the product refrigeration circulation tank for subsequent treatment, and the concentrated effluent is directly discharged.

2、 Design basis

This technology belongs to the field of ultrafiltration membrane concentration material treatment, involving the optimization of traditional plasma membrane treatment processes and the improvement of membrane efficiency and service life. Fresh plasma has undergone excellent anticoagulation pretreatment to ensure that there are no flocculent substances in the plasma before entering the membrane system; Fresh blood that has undergone anticoagulation treatment and refrigerated transportation at the slaughterhouse must be separated from plasma and blood cells at the ultrafiltration membrane concentration site using a high-speed tube centrifuge; The color of the separated plasma is relatively light.

Technical advantages of plasma protein membrane concentration process:

1. The membrane concentration process is room temperature concentration, and there is no phase change during the concentration process. Under the same conditions, the concentration energy consumption is much lower;

2. The membrane concentration process is concentrated at room temperature, which can prevent the denaturation and inactivation of thermosensitive proteins while effectively preventing plasma from freezing at high temperatures;

3. During membrane concentration, some inorganic salts are removed, reducing ash content and effectively improving product quality;

4. The membrane concentration system adopts a cross flow process, which can effectively solve the problem of membrane fouling and blockage;

5. Membrane equipment occupies a small area, has a long service life, and reduces production costs and investment;

6. High degree of automation, clean production, reduced labor intensity, safe and reliable.